Paul B Fisher Selected Research

AD 5

1/2018	Cancer terminator viruses (CTV): A better solution for viral-based therapy of cancer.
1/2016	mda-7/IL-24 Induces Cell Death in Neuroblastoma through a Novel Mechanism Involving AIF and ATM.
1/2014	Enhanced prostate cancer gene transfer and therapy using a novel serotype chimera cancer terminator virus (Ad.5/3-CTV).
11/2013	Combining histone deacetylase inhibitors with MDA-7/IL-24 enhances killing of renal carcinoma cells.
8/2013	Histone deacetylase inhibitors interact with melanoma differentiation associated-7/interleukin-24 to kill primary human glioblastoma cells.
5/2012	Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells.
3/2011	A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.
12/2010	Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery.
6/2010	Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma.

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Paul B Fisher Research Topics

Disease

235	Neoplasms (Cancer) 12/2023 - 07/2002
129	Melanoma (Melanoma, Malignant) 12/2023 - 01/2002
44	Neoplasm Metastasis (Metastasis) 11/2023 - 11/2004
35	Infections 11/2021 - 01/2002
30	Prostatic Neoplasms (Prostate Cancer) 11/2023 - 11/2003
26	Glioma (Gliomas) 01/2018 - 02/2003
25	Breast Neoplasms (Breast Cancer) 01/2023 - 06/2005
22	Hepatocellular Carcinoma (Hepatoma) 12/2023 - 09/2008
21	Carcinoma (Carcinomatosis) 01/2019 - 03/2002
19	Glioblastoma (Glioblastoma Multiforme) 03/2020 - 07/2003
17	Pancreatic Neoplasms (Pancreatic Cancer) 11/2023 - 01/2005
17	Carcinogenesis 01/2023 - 01/2005
10	Inflammation (Inflammations) 12/2023 - 10/2004
8	Ovarian Neoplasms (Ovarian Cancer) 07/2012 - 08/2004
7	Leukemia 03/2020 - 03/2010
6	Colorectal Neoplasms (Colorectal Cancer) 02/2021 - 11/2007
6	Virus Diseases (Viral Diseases) 01/2016 - 02/2007
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 02/2003
5	Neuroblastoma 11/2021 - 06/2009
5	Renal Cell Carcinoma (Grawitz Tumor) 11/2013 - 07/2003
5	Kidney Neoplasms (Kidney Cancer) 01/2013 - 05/2009
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2013 - 12/2003
5	Lung Neoplasms (Lung Cancer) 06/2012 - 05/2004
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2011 - 02/2007
4	Adenocarcinoma 11/2023 - 09/2008
4	Brain Neoplasms (Brain Tumor) 10/2017 - 02/2003
3	Hypoxia (Hypoxemia) 01/2021 - 12/2009

Drug/Important Bio-Agent (IBA)

85	Proteins (Proteins, Gene)FDA Link 10/2023 - 01/2002
62	InterleukinsIBA 12/2021 - 08/2003
57	CytokinesIBA 01/2022 - 02/2003
32	SynteninsIBA 11/2023 - 11/2004
14	Messenger RNA (mRNA)IBA 02/2015 - 01/2002
13	Interleukin-10 (Interleukin 10)IBA 12/2021 - 05/2004
13	Phosphotransferases (Kinase)IBA 07/2011 - 03/2004
11	SyndecansIBA 12/2023 - 11/2004
11	Small Interfering RNA (siRNA)IBA 12/2015 - 05/2007
10	Carrier Proteins (Binding Protein)IBA 12/2023 - 10/2017
10	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 07/2003
10	mezereinIBA 11/2020 - 01/2002
10	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017 - 12/2003
9	Biomarkers (Surrogate Marker)IBA 01/2023 - 06/2012
9	Transcription Factors (Transcription Factor)IBA 03/2022 - 01/2005
9	ErbB Receptors (EGF Receptor)IBA 01/2020 - 08/2004
9	AD 5IBA 01/2018 - 06/2010
9	CeramidesIBA 09/2011 - 05/2009
8	Paclitaxel (Taxol)FDA LinkGeneric 01/2023 - 02/2011
8	NF-kappa B (NF-kB)IBA 01/2017 - 10/2004
8	CaspasesIBA 01/2016 - 02/2008
7	EnzymesIBA 01/2023 - 12/2002
7	AntigensIBA 01/2021 - 01/2007
7	Histone Deacetylase InhibitorsIBA 01/2016 - 12/2007
7	Glutamic Acid (Glutamate)FDA Link 01/2015 - 02/2003
7	Interferon Type IIBA 03/2014 - 10/2003
7	Sorafenib (BAY 43-9006)FDA Link 10/2013 - 09/2008
7	Polyribonucleotide Nucleotidyltransferase (Polynucleotide Phosphorylase)IBA 01/2013 - 07/2003
6	Double-Stranded RNA (RNA, Double Stranded)IBA 11/2023 - 01/2002
6	InterferonsIBA 12/2021 - 01/2002
6	Interferon-betaIBA 11/2020 - 01/2002
6	MicroRNAs (MicroRNA)IBA 01/2019 - 06/2010
6	Caspase 3 (Caspase-3)IBA 01/2017 - 04/2008
6	LigandsIBA 01/2017 - 03/2004
6	Tretinoin (Retinoic Acid)FDA LinkGeneric 08/2015 - 07/2006
6	1,1',6,6',7,7'- hexahydroxy- 3,3'- dimethyl- N5- (2- phenylpropyl)- N5'- (2- phenylpropyl)- 2,2'- binaphthyl- 5,5'- dicarboxamideIBA 06/2015 - 05/2010
6	p38 Mitogen-Activated Protein KinasesIBA 01/2014 - 07/2002
6	adenovirus receptorIBA 01/2011 - 07/2003
5	Interleukin-6 (Interleukin 6)IBA 01/2022 - 10/2004
5	Antiviral Agents (Antivirals)IBA 01/2020 - 07/2006
5	Micrococcal NucleaseIBA 09/2019 - 04/2012
5	AgarIBA 03/2015 - 08/2004
5	VaccinesIBA 01/2014 - 05/2008
5	RNA Helicases (RNA Helicase)IBA 03/2008 - 01/2002
4	RNA (Ribonucleic Acid)IBA 12/2023 - 10/2004
4	Matrix Metalloproteinases (MMPs)IBA 10/2023 - 10/2004
4	CateninsIBA 02/2021 - 12/2013
4	Indicators and Reagents (Reagents)IBA 01/2021 - 10/2004
4	Tamoxifen FDA LinkGeneric 01/2018 - 01/2013
4	Hormones (Hormone)IBA 03/2016 - 11/2003
4	Drug CombinationsIBA 03/2014 - 10/2006
4	Peptide Hydrolases (Proteases)FDA Link 03/2014 - 04/2007
4	Caspase 9IBA 10/2013 - 04/2008
4	Antineoplastic Agents (Antineoplastics)IBA 01/2013 - 02/2007
4	tanespimycin (17AAG)IBA 03/2011 - 01/2008
4	Endoplasmic Reticulum Chaperone BiPIBA 12/2010 - 08/2006
4	Vorinostat FDA Link 08/2010 - 12/2007
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2023 - 11/2012
3	IntegrinsIBA 01/2023 - 06/2013
3	insulin-like growth factor binding protein-related protein 1IBA 01/2023 - 11/2011
3	Docetaxel (Taxotere)FDA Link 01/2023 - 10/2006
3	interleukin-24 (ST16)IBA 01/2022 - 01/2002
3	Cisplatin (Platino)FDA LinkGeneric 12/2021 - 02/2010
3	Cadherins (E-Cadherin)IBA 02/2021 - 11/2016
3	Beclin-1IBA 01/2018 - 05/2010
3	GoldIBA 01/2018 - 12/2015
3	CarcinogensIBA 01/2017 - 06/2015
3	Insulin-Like Growth Factor Binding ProteinsIBA 01/2017 - 04/2013

Therapy/Procedure

129	Therapeutics 11/2023 - 01/2002
27	Drug Therapy (Chemotherapy) 01/2023 - 07/2003
13	Immunotherapy 01/2023 - 10/2005
12	Radiotherapy 01/2023 - 07/2003
4	Injections 12/2021 - 09/2006